How it Works:

Streamlining DNA Library Preparation for NGS Modern high-throughput sequencing technology has led to a boom in sequencing projects spanning a wide range of research. High-throughput sequencing methods like next generation sequencing (NGS) are now a critical tool for both basic and clinical research, as evidenced by the leap from 236 NGS PubMed citations in 2009 to 1,878 in 2013. However, in many cases genomic DNA can’t be accurately sequenced by NGS, a frustrating challenge for researchers. NGS requires input DNA to first be chopped into short fragments, and then sequences the fragments to determine the order of the bases.