Whole exome sequencing is a powerful tool for the identification of disease-causing mutations. It is used in the diagnosis of rare and common diseases, including cancer and severe Mendelian disorders.
Your research approach is based on this essential part of the human genome and you have precious samples? Our low amount input approach enables researchers to analyse samples, while retaining sufficient material for future tests.
Your research produces only small batch sizes? We also analyse single samples providing you with the results in record breaking speed.
You rely on pre-determined coverage? We guarantee your chosen coverage of at least 30x, 60x or even 120x.
You always strive for the best? We do the same by using mechanical shearing for great uniformity of coverage and by following the SureSelectXT post capture protocol for highest enrichment efficiency.
Focus on the essential! Our InView Human Exon is the perfect solution for fast variant detection and translational studies. Choose between three different delivery times according to your needs. Our ISO 17025 accredited Genome and Diagnostics Centre meets the high standards in clinical research and guarantees you the data quality you expect for your project.
Choose your InView Human Exon solution today!
More and more prevalent diseases, like cancer or diabetes, are known to be influenced by epigenetic factors. For example, during carcinogenesis a change occurs in the DNA methylation pattern within CpG islands. The characterisation of the methylation could be used to identify biomarkers for early cancer detection.
You are interested in the growing field of epigenomics? Our ISO 17025 accredited Genome and Diagnostics Centre meets these high standards in clinical research and follows the recommendations of the International Human Epigenome Consortium (IHEC). Build on our long-term experience in isolating circulating cell-free DNA, as well as Whole Genome (BS-Seq) and Reduced Representation Bisulfite Sequencing (RRBS-Seq) proven in renowned cancer research projects and publicly funded projects, such as EpiFemCare.
You need to "dig deeper" into the methylome? GATC Biotech’s InView™ Epigenome offers a standardised solution with high-end bisulfite conversion rate and allows the identification of methylation patterns at true base level resolution.
You need to be flexible? You can scale the coverage according to your requirements.
You want to deal with high-quality raw data yourself or receive our comprehensive Data Analysis Report with ready-to-publish data? Our optimised workflow and proprietary BioIT pipeline ensures the right solution for your approach.
There is much to take into consideration for gene expression and gene regulation studies. No matter if you are about to detect and identify common or rare transcripts, analyse gene expression, determine alternative splicing events or seek information about structure and orientation of the transcript - InView Transcriptome is your solution. InView Transcriptome can be ordered in three different packages EXPLORE, ADVANCE and DISCOVER.
EXPLORE is the right choice, if you want to explore gene expression under specific conditions and compare expression levels of different samples with a guaranteed read coverage of 30 million.
ADVANCE allows you to dig deeper with the possibility of monitoring even rare transcripts. For this package we also increased the number of guaranteed single reads (50 bp) to 60 million.
DISCOVER offers you the most comprehensive analysis of expression level, sequence and structure. Our strand-specific RNA library combined with Illumina’s 100 bp paired end sequencing (60 million reads coverage guaranteed) enables the detection of novel transcripts and splicing variants in great detail and with a high sensitivity.
InView™ Human Exon – Fastest variant detection for clinical research and translational studies.
Exome enrichment and massively parallel sequencing of the coding regions is a versatile and economic tool for researches who want to identify relevant disease-causing mutations. InView™ 2-weeks Exome is a highly standardised complete solution for clinical and medical researchers to help them answer important questions faster.
- fast access within 10 business days, starting from one sample
- applicable for genomic DNA and various other sources (tissue, cells, blood and FFPE sample)
- special protocol for low-input samples (please refer to Service & Specifications)
InView™ 2-weeks Exome is a result of our customer-driven innovation process in close collaboration with partners from DKFZ (Deutsches Krebsforschungszentrum) or NCT (Nationales Centrum für Tumorerkrankungen) in Heidelberg, Germany.
"GATC Biotech proved itself to be a reliable sequencing partner..." Prof. Dr. Peter Lichter, Head of Molecular Genetics, DKFZ, Heidelberg
InView™ 2-weeks Exome is the solution for your cutting-edge clinical research.
Brandnew in the InView™ product pipeline: Microbiome Profiling 2.0 will soon be available for your fungal microbiome, too. GATC Biotech offers ITS analysis using Illumina technology and allowing parallel pooling of up to 96 samples. Benefit from extended 2 x 300 bp paired-end sequencing for higher specificity and a sufficient data output for precise profiling of organisms down to species level.
Coming soon… Watch out for GATC Biotech at the EMBO GENOMES in Paris!
GATC InView™ – Zielgerichtete Next Gen Sequencing-basierte Lösungen für spezifische wissenschaftliche Fragestellungen
Die InView™-Applikationen der GATC Biotech bieten, maßgeschneidert für Ihr spezifisches Wissenschaftsgebiet, umfassende Next Generation Sequencing-basierte Analysekonzepte. Dieses Serviceangebot umfasst alle Schritte von der Qualitätskontrolle, über die Sequenzierung bis hin zur bioinformatischen Analyse.
Mit einer Kombination aus hochwertigen zertifizierten Service-Standards und fokussierten Arbeitsabläufen garantieren wir Ihnen höchste Datenqualität und eine effiziente Durchführung ihrer Projekte. So sorgt ein engagiertes Projektmanagement-Team, bestehend aus wissenschaftlichen Spezialisten und Bioinformatikern, für eine kontinuierliche Betreuung und Überwachung jedes einzelnen Projektschritts.
GATC Biotech bietet bereits seit 2006 Next Generation Sequencing-Services an. Um unseren Kunden die innovativsten Lösungen für ihre Forschungsfragen zu bieten, investieren wir stets frühzeitig in vielversprechende Technologien und neueste Trends.
Als von Agilent und Illumina zertifizierter Servicedienstleister garantieren wir, dass unsere Labormethoden den neuesten Qualitätsstandards entsprechen. Seit Juni 2012 sind die Next Generation Sequencing-Plattformen Illumina HiSeq, Illumina MiSeq, Roche FLX und PacBio RS II offiziell von der Deutschen Akkreditierungsstelle DAkkS akkreditiert - nach den internationalen ISO-Normen 17025.
Optimierte LIMS-gesteuerte Workflows
• Barcode-Etikettierung ermöglicht eine eindeutige Identifizierung Ihrer Proben
• Online-Nachverfolgung in Echtzeit ermöglicht ein hohes Maß an Transparenz des gesamten Sequenzierungs-Projekts
• Zuverlässige und kurze Lieferzeiten in Anhängigkeit von der Komplexität des Projekts
This years’ Analytica attracted more than 34,400 visitors to Munich. The exhibitors reached a record number of 1,142 companies from 40 participating countries. GATC Biotech as one of them, would like to grab the opportunity and say thank you very much for the fruitful discussions and and the trust you place in our company.
In Munich, our brand new InView™ Transcriptome products were taken centre stage. InView™ Transcriptome EXPLORE, ADVANCE and DISCOVER are perfectly suited for your RNA-Seq projects. The InView™ product family offers you highly standardised packages which are scaled to fit any application – no matter if you are working on, e.g. transcriptome studies, microbiome profiling, de novo genome assembly or human exome studies. Save time and effort by choosing one of our best practice InView™ products, which contain what’s needed for a successful completion of your sequencing project. Learn more about service and specifications, deliverables and additional benefits at www.gatc-biotech.com.
Also the ‚Deutsche Biotechnolgietage‘ last week, once again provided a scientific platform for networking across the German biotech landscape. It was a great opportunity for established and emerging biotech companies to discuss current research concerns.
As one of the Platin sponsors, GATC Biotech enjoyed the many interesting discussions at our booth and the talks on present status and future prospects of biotech hot topics, such as individualised medicine.
Im April feiern wir den 15. Geburtstag unseres GATC Böxles!
Feiern Sie mit uns. Basteln Sie für unseren Fotowettbewerb einen Böxle-Freund und schicken Sie diesen nach Köln zur "Grand Parade" oder finden Sie in unserem Geburtstagsgewinnspiel ein "Goldenes Böxle".
RNA-Seq is a powerful method for exploring, quantifying, profiling and discovering RNA transcripts all over the transcriptome. Experience unbiased transcriptome information without any prior assumption or sequence knowledge required. Compared to microarray studies, RNA-Seq allows a more sensitive real-time detection of genes, transcripts, and differential expression. Higher throughput of RNA-Seq, flexible project design and continuous sequencing improvements lead to faster and high-end results.
To fulfill these demands GATC Biotech has launched three products for transcriptome studies:
InView™ Transcriptome EXPLORE, ADVANCE and DISCOVER
Highly standardised, scaled to fit any application and need as well as guaranteed output of read numbers per package, are only three of numerous benefits of these InView™ Transcriptome products.
To give full service, we are even able to offer a one-stop solution for de novo transcriptome sequencing based on PacBio RS II or MiSeq technology.
Save time and effort by choosing one of our best practice InView™ products, which contain what’s needed for a successful completion of your sequencing project. Learn more about service and specifications, deliverables and additional benefits here.
Delivering Great, Accurate, Time saving and Consistent service for more than 24 years. A clear commitment for Cologne was made already 2 years ago. This allowed us to gain a European-wide logistic solution ensuring the provision of our services to you today. Our European Custom Sequencing Centre works around the clock in order to analyse your samples. For processing approx. 12,000 samples per day, no matter if arriving in tubes or 96 well plates, we keep a fleet of Hamilton robots and 16 ABI* 3730XL busy. We deliver high quality data already within the next working day after sample receipt – and even faster with NightXpress.
So imagine you on a 15 hour journey from Zurich to Praha by train with the City Night Liner or your sample with GATC Biotech’s NightXpress from all over Europe to Cologne and back to you in 15 hours, too. Cologne with its central location in Europe and serving as a turntable in freight traffic is the perfect place wherever fast logistics is essential.
Thank you very much to all our loyal customers and welcome to all who are looking for an outstanding sequencing service. Click here to make Cologne YOUR sequencing centre of Europe, too.
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