VTU Technology will be exhibiting at the BIO 2014 International Convention, June 23-26, San Diego, CA.
We will be happy to provide you more information on our outstanding Pichia pastoris protein expression platform & services and we are looking forward to giving you insights into our latest technology developments.
Please feel free to contact us directly or via the event´s partnering system for the arrangement of a meeting or just see us at our booth at the Austrian Pavilion, 4407.
Cutting-edge, exclusive, proprietary technologies and know-how are the basis for the broadest toolbox and most versatile technology platform available for Pichia pastoris recombinant protein expression / production enabling highest productivities ever reported.
We guarantee tight development timelines and deliver production processes being
robust and readily scalable
safe - no risk of viral or endotoxin contamination
accompanied by simplified protein purification procedures
Services from VTU Technology
High speed expression strain development
Upstream process development and optimization
Downstream and analytical process development
Small-scale production of purified non-GMP material
Sound technology & data transfer to our customers
Outlicensing opportunities fo
- Human serum albumin (HSA)
- Human serum transferrin (HST)
- HSA-fusion proteins
- Cell culture proteins
With more than 300 employees and 15 sites, VTU is now competing in the premier league of technology service providers.
The VTU Group - planners, consultants and suppliers of high-tech process plants for industry - will have more than 300 employees as of July 2013, which means that a small company of process engineering consultants, established by Dr. Michael Koncar in 1990, has developed into a European technology company. VTU takes care of a large number of substantial customers, including major international pharmaceutical and chemical companies, at 15 current sites in Austria, Germany, Italy, Switzerland and Romania.
VTU is now putting the expertise gathered in the company’s early stages from the planning of pharmaceutical and biodiesel plants into practice internationally as an engineering specialist and technology service provider for the pharmaceutical and biotechnology, chemical and metallurgy, crude oil and natural gas industries with the addition of the power engineering sector.
“We have always relied on highly qualified and highly-motivated staff in all our activities. We have also always endeavoured at all times to offer the team a corporate environment where delivering peak performances is fun even when times are hard.” Quote by Dr. Michael Koncar, company founder and Holding MD
VTU is banking on further steady growth based on long-term collaborative customer relationships. Increases to date have been in the form of organic growth generated from the company’s own efforts. The management is characterised by employees who have worked at VTU for many years and who are responsible for the company’s strategic alignment. Sustainable business management takes precedence over profit maximisation and the company has worked very successfully for many years by taking this fundamental approach.
By applying VTU´s Pichia pastoris protein expression technology researchers at VTU have repeatedly demonstrated their ability to rapidly produce a wide range of different proteins (serum proteins, cytokines, Fabs and other antibody derived fragments, scaffold proteins, HSA-fusion proteins, Fc-fusion proteins and enzymes) by full exploitation of VTU´s protein expression technologies and optimized procedures for high-throughput expression strain development.
VTU´s expression technology platform is based on the following technological advances:
1. Proprietary technology - VTU´s exclusive AOX1 promoter libraries provide an unprecedented genetic diversity with superior regulatory properties for fine tuning of gene expression by selecting the perfect match of promoter/target combinations.
2. FTO tools - VTU´s in-house modular plasmid system and platform strains enable the optimization of protein production and provide more flexibility to fulfill the different requirements of various expression tasks.
3. Optimized procedures - VTU´s team applies highly elaborated and time-saving procedures, based on a pool approach for transformation and a high-throughput cultivation - & screening regime allowing for maximization of output.
Key components of VTU´s Pichia pastoris protein expression platform
VTU Technology, a leading expert in the field of Pichia pastoris protein expression and one of the main sponsors of the upcoming Pichia 2014 event (March 2-5, San Diego, CA USA), will be presenting its latest findings and exciting technology developments.
To date, VTU has established a broad range of technologies and know-how for the fast-track generation of high performance Pichia protein production strains and processes. Exclusive proprietary technologies and profound experience of the VTU team lead to competitive production processes for a wide range of recombinant proteins.
Don´t miss the opportunity to attend the following talks providing insights into the most versatile and powerful Pichia pastoris protein expression platform:
Monday, March 3rd, 2014, 4:00 p.m.: Dr. Iskandar Dib, Principal Scientist Process Development & Analytics
Short Lecture 15: Targeted process optimization and scale up to industrial scale with 2nd generation AOX1 promoter variants
Tuesday, March 4th, 2014, 2.00 p.m.: Dr. Roland Weis, Head of Operations
Short Lecture 25: Uniform GlcNAc2Man5-decorated proteins by Pichia pastoris: achievements in high-level production and characterization
Tuesday, March 4th, 2014, 3.30 p.m.: Dr. Aid Atlic, Research Scientist Development & Fermentation
Short lecture 29: Half-life extension of a chemokine by fusion to HSA: implications on producibility and in vitro / in vivo characteristics of the fusion protein
Find more details in the attached Document.
Kongresse und Messen 2014
Pichia 2014, 2-5 March, San Diego, California, USA
7th Annual Proteins & Antibodies Congress 2014, 3-4 April, London, UK
BIO International Convention 2014, 23-26 June, San Diego, California, USA
7th international Congress on Biocatalysis - biocat 2014, Hamburg, 31 August – 4 September, Germany
CPhI Worldwide 2014, 7-9 October, Paris, France
Bio Europe 2014, 3-5 November, Frankfurt, Germany
Profit from a proven and exclusive technology platform applied by a highly skilled team
VTU Technology will be attending PEPTALK 2014, Palm Springs, California and will be available to provide more information on its oustanding Pichia pastoris protein expression platform & services and latest technology developments.
Listen to VTU´s Head of Operations, Dr. Roland Weis speaking about "Uniform GlcNAc2Man5-Decorated Proteins by Pichia pastoris: Achievements in High-Level Production and Characterization"; January 13, 12.15 p.m, Pipeline 5
Engineering Genes, Vectors, Constructs and Clones
Heterogeneous N-linked glycan profiles on therapeutic proteins represent a regulatory disadvantage paired with an elevated workload to identify the respective glycan distribution from batch to batch. Next to its extraordinary secretion capacity, the established recombinant production host Pichia pastoris now features homogeneous N-glycan structures (GlcNAc2Man5) for reliable high-level production of demanding proteins. Case studies of the biological implications of these glycans on human serum proteins will be presented.
Please feel free to contact us directly for the arrangement of a meeting.